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Granuloma inguinale (also known as donovanosis) is a bacterial disease caused by ''Klebsiella granulomatis'' characterized by ulcerative genital lesions. It is endemic in many less developed regions. It is also known as donovanosis, granuloma genitoinguinale,〔 granuloma inguinale tropicum,〔 granuloma venereum, granuloma venereum genitoinguinale,〔 lupoid form of groin ulceration,〔 serpiginous ulceration of the groin,〔 ulcerating granuloma of the pudendum,〔 and ulcerating sclerosing granuloma. The disease often goes untreated because of the scarcity of medical treatment in the countries in which it is found. In addition, the painless genital ulcers can be mistaken for syphilis. The ulcers ultimately progress to destruction of internal and external tissue, with extensive leakage of mucus and blood from the highly vascular lesions. The destructive nature of donovanosis also increases the risk of superinfection by other pathogenic microbes. ==Classification and terminology== The first known name for this condition was "serpiginous ulcer", which dates to 1882. The proper clinical designation for donovanosis is now "granuloma inguinale".〔 A granuloma is a nodular type of inflammatory reaction, and inguinale refers to the inguinal region, which is commonly involved in this infection. The disease is commonly known as donovanosis, after the Donovan bodies which are a diagnostic sign. The causative organism, ''Klebsiella granulomatis'', was called ''Calymmatobacterium granulomatis'', and some sources still use this classification,〔 〕 from the Greek ''kalymma'' (a hood or veil), referring to the lesions that contain the bacteria. Prior to this, it was called ''Donovania granulomatis'', named after the Donovan bodies.〔 The specific name ''granulomatis'' refers to the granulomatous lesions. The organism was recently reclassified under the genus ''Klebsiella'',〔 * 〕 a drastic taxonomic change since it involved changing the organism's phylum. However, polymerase chain reaction techniques using a colorimetric detection system showed a 99% similarity with other species in the ''Klebsiella'' genus. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Granuloma inguinale」の詳細全文を読む スポンサード リンク
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